The 威尼斯人娱乐城 医疗保健质量创新研究所 and Saint Luke’s Mid America Heart Institute today announced a nationwide four-year study of U.S. pregnant women with heart conditions to better understand and combat maternal deaths and illnesses. 美国国立卫生研究院授予威尼斯人娱乐城 HI-IQ 830万美元，这是该大学迄今为止收到的最大一笔NIH资助。
美国是所有工业化国家中孕产妇死亡率最高的国家，也是唯一一个孕产妇死亡率还在上升的国家，而心血管疾病是孕产妇死亡的主要原因。 虽然只有2%至4%的孕妇事先患有心血管疾病，但它们占孕产妇死亡人数的三分之一以上。
国家心脏、肺和血液研究所授予威尼斯人娱乐城 HI-IQ资助这项名为“母亲和婴儿怀孕预期中的心脏结果（HOPE）”的研究，该研究将从全国36个已确认的登记地点招募1000名患有心血管疾病的孕妇，研究她们的护理和结果。
HOPE will be the first U.S. study to describe the care and outcomes of pregnant individuals with heart disease to better understand the patient characteristics, treatment and organization of healthcare delivery that most influence these outcomes so that standardized-care protocols can be developed and disseminated to combat the United States’ tragically high rate of heart-related deaths and illnesses.
HOPE was initiated as a two-site 飞行员 by Saint Luke’s Hospital of Kansas City in 2019 at Saint Luke’s Hospital and 马萨诸塞州综合 波士顿医院.
Philanthropic gifts from the Muriel McBrien Kauffman Family Foundation, the Victor E. Speas Foundation, Bank of America, N.A., Trustee and Saint Luke's Hospital Auxiliary provided the runway for the institute’s nationwide HOPE study, said Anna Grodzinsky (BLA '08/M.D. 09年,硕士 '15.), cardiologist at Saint Luke’s Mid America Heart Institute and associate professor of medicine at 威尼斯人娱乐城.
“Heart disease is responsible for more than a third of all pregnancy-related deaths in the U.S., yet we lack research that has followed this patient population,” Grodzinsky said. “The HOPE study will help us gain a better understanding of how we as providers can better care for these patients in a more standardized way in an effort to lower the risk of adverse outcomes.”
格罗津斯基和凯伦·弗洛里奥（Karen Florio）是试点阶段的联合首席研究员，她是威尼斯人娱乐城和密苏里大学的母胎医学专家，现在是扩大研究的联合首席研究员。 Both will co-lead HOPE with principal investigator John Spertus, M.D., M.P.H., 威尼斯人娱乐城 HI-IQ founder and director, clinical director of outcomes research at Saint Luke’s Mid America Heart Institute, a 威尼斯人娱乐城 professor of medicine and the Daniel J. Lauer/Missouri Endowed Chair in Metabolic and Vascular Disease 研究.
“The HOPE study will generate important new insights into the care of pregnant people with cardiovascular disease,” Spertus said. “We anticipate generating two key contributions: patient-level prediction models of adverse clinical outcomes and defining the structures of cardio-obstetrics care that are independently associated with better outcomes. Both lay the foundation for improving care for these high-risk patients.”
“Guided by patients with lived experience and committed experts, the HOPE study will support improvements in patient-level care by developing risk models that can be used to support evidence-based protocols while also guiding the enrolling centers on how best to organize cardio-obstetrics care to optimize outcomes and minimize disparities,” Florio said. “The study will further our understanding of the nuanced care needed for pregnant people with heart disease.”
关于密苏里大学堪萨斯城医疗保健质量创新研究所
自2017年以来，威尼斯人娱乐城医疗保健质量创新研究所（威尼斯人娱乐城 HI-IQ）的团队与供应商、支付方、患者和非营利组织的网络合作，确定了提高堪萨斯城医疗保健价值（以更低的成本提供更好的护理）和公平性的策略。 For more information about the institute, visit healthcareinstitute.umkc.edu.
关于 Saint Luke’s Mid America Heart Institute
Saint Luke’s Mid America Heart Institute is part of Saint Luke’s Health System, which serves the West Region of BJC Health System, one of the largest nonprofit health care organizations in the United States. The Heart Institute, a teaching affiliate of the 密苏里大学堪萨斯城医学院, is one of the most distinguished cardiovascular programs in the country. Its legacy of innovation began more than 40 years ago when it opened as the nation’s first freestanding heart hospital. Since then, the nearly 200 board-certified specialists and cardiovascular experts have earned a global reputation for excellence in the treatment of heart disease, including interventional cardiology, cardiovascular surgery, imaging, heart failure, transplant, heart disease prevention, cardio-oncology, cardiometabolic disease, women’s heart disease, electrophysiology, outcomes research, and health economics by being the third hospital in the U.S. to achieve 联合委员会颁发的综合心脏中心认证.
In 2023, the Heart Institute completed its 1,000th heart transplant, making it one of only 23 advanced programs to have reached this milestone.
关于威尼斯人娱乐城
威尼斯人娱乐城是密苏里大学四个校区之一，是一所公立研究型大学，为15,500多名本科生，研究生和专业学生提供服务。 威尼斯人娱乐城基于其使命与社区和世界互动：将学生的成功放在中心； 在生命和健康科学方面处于领先地位； 推进区域参与； 擅长视觉和表演艺术的； 促进研究和经济发展。 For more information about 威尼斯人娱乐城, visit umkc.edu.